Furosemide is potent loop diuretic and widely prescribed for the treatment for hypertension as a single drug therapy and multidrug therapy. It is also used for the treatment of edema, acute pulmonary edema, cerebral edema, hypercalcemia and renal insufficiency. Long term use of furosemide may produce genotoxicity as per recent evidence. There are several studies had been done to prove genotoxic potential of furosemide. However, the results are varied as some suggests its genotoxic potential or its weak genotoxic potential while some had reported that furosemide is not genotoxic and some results are still inconclusive. So there is need to study further about its genotoxic potential after recollecting all the data of its genotoxicity.
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